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Immunization of mice with soluble lysate of interferon gamma expressing Plasmodium berghei ANKA induces high IFN-γ production

BACKGROUND: Efforts in search of lasting malaria vaccine have led to the development of transgenic rodent malaria parasites. As a result, wild type Plasmodium berghei ANKA (WTPbA) has recently been transformed to express mouse interferon gamma (mIFN-γ). The immunomodulatory effect of this transgenic...

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Detalles Bibliográficos
Autores principales: Taylor, Ebenezer, Onditi, Faith, Maina, Naomi, Ozwara, Hastings
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531070/
https://www.ncbi.nlm.nih.gov/pubmed/28883981
http://dx.doi.org/10.1186/s40794-017-0053-1