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Proteolytic processing of the L-type Ca (2+) channel alpha (1)1.2 subunit in neurons

Background: The L-type Ca2+ channel Cav1.2 is a prominent regulator of neuronal excitability, synaptic plasticity, and gene expression. The central element of Cav1.2 is the pore-forming α (1)1.2 subunit. It exists in two major size forms, whose molecular masses have proven difficult to precisely det...

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Detalles Bibliográficos
Autores principales: Buonarati, Olivia R., Henderson, Peter B., Murphy, Geoffrey G., Horne, Mary C., Hell, Johannes W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531164/
https://www.ncbi.nlm.nih.gov/pubmed/28781760
http://dx.doi.org/10.12688/f1000research.11808.2