Hepatic overexpression of cAMP-responsive element modulator α induces a regulatory T-cell response in a murine model of chronic liver disease

OBJECTIVE: Th17 cells are a subset of CD4(+) T-helper cells characterised by interleukin 17 (IL-17) production, a cytokine that plays a crucial role in inflammation-associated diseases. The cyclic AMP-responsive element modulator-α (CREMα) is a central mediator of T-cell pathogenesis, which contribu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuttkat, Nadine, Mohs, Antje, Ohl, Kim, Hooiveld, Guido, Longerich, Thomas, Tenbrock, Klaus, Cubero, Francisco Javier, Trautwein, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531221/
https://www.ncbi.nlm.nih.gov/pubmed/27686093
http://dx.doi.org/10.1136/gutjnl-2015-311119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531221/
https://www.ncbi.nlm.nih.gov/pubmed/27686093
http://dx.doi.org/10.1136/gutjnl-2015-311119

Ejemplares similares