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Hepatic overexpression of cAMP-responsive element modulator α induces a regulatory T-cell response in a murine model of chronic liver disease

OBJECTIVE: Th17 cells are a subset of CD4(+) T-helper cells characterised by interleukin 17 (IL-17) production, a cytokine that plays a crucial role in inflammation-associated diseases. The cyclic AMP-responsive element modulator-α (CREMα) is a central mediator of T-cell pathogenesis, which contribu...

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Detalles Bibliográficos
Autores principales:	Kuttkat, Nadine, Mohs, Antje, Ohl, Kim, Hooiveld, Guido, Longerich, Thomas, Tenbrock, Klaus, Cubero, Francisco Javier, Trautwein, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2017
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531221/ https://www.ncbi.nlm.nih.gov/pubmed/27686093 http://dx.doi.org/10.1136/gutjnl-2015-311119

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