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Mechanosensing is critical for axon growth in the developing brain

During nervous system development, neurons extend axons along well-defined pathways. The current understanding of axon pathfinding is based mainly on chemical signalling. However, growing neurons interact not only chemically but also mechanically with their environment. Here we identify mechanical s...

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Detalles Bibliográficos
Autores principales: Koser, David E., Thompson, Amelia J., Foster, Sarah K., Dwivedy, Asha, Pillai, Eva K., Sheridan, Graham K., Svoboda, Hanno, Viana, Matheus, da F. Costa, Luciano, Guck, Jochen, Holt, Christine E., Franze, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531257/
https://www.ncbi.nlm.nih.gov/pubmed/27643431
http://dx.doi.org/10.1038/nn.4394