Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment

Individual cells take lineage commitment decisions in a way that is not necessarily uniform. We address this issue by characterising transcriptional changes in cord blood-derived CD34+ cells at the single-cell level and integrating data with cell division history and morphological changes determined...

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Detalles Bibliográficos
Autores principales: Moussy, Alice, Cosette, Jérémie, Parmentier, Romuald, da Silva, Cindy, Corre, Guillaume, Richard, Angélique, Gandrillon, Olivier, Stockholm, Daniel, Páldi, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531424/
https://www.ncbi.nlm.nih.gov/pubmed/28749943
http://dx.doi.org/10.1371/journal.pbio.2001867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531424/
https://www.ncbi.nlm.nih.gov/pubmed/28749943
http://dx.doi.org/10.1371/journal.pbio.2001867

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