The role of tumour suppressor PDCD4 in beta cell death in hypoxia

OBJECTIVE: Hypoxia is known to induce pancreatic beta cell dysfunction and apoptosis. Changes in Programmed Cell Death Gene 4 (PDCD4) expression have previously been linked with beta cell neogenesis and function. Our aim was to investigate the effects of hypoxia on cell viability, PDCD4 expression a...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Marriott, Claire E., Alhasawi, Nouf F., Bone, Adrian J., Macfarlane, Wendy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531437/
https://www.ncbi.nlm.nih.gov/pubmed/28750063
http://dx.doi.org/10.1371/journal.pone.0181235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531437/
https://www.ncbi.nlm.nih.gov/pubmed/28750063
http://dx.doi.org/10.1371/journal.pone.0181235

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