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The role of tumour suppressor PDCD4 in beta cell death in hypoxia
OBJECTIVE: Hypoxia is known to induce pancreatic beta cell dysfunction and apoptosis. Changes in Programmed Cell Death Gene 4 (PDCD4) expression have previously been linked with beta cell neogenesis and function. Our aim was to investigate the effects of hypoxia on cell viability, PDCD4 expression a...
Autores principales: | Kumar, Sandeep, Marriott, Claire E., Alhasawi, Nouf F., Bone, Adrian J., Macfarlane, Wendy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531437/ https://www.ncbi.nlm.nih.gov/pubmed/28750063 http://dx.doi.org/10.1371/journal.pone.0181235 |
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