Pancreatic cancer cell/fibroblast co-culture induces M2 like macrophages that influence therapeutic response in a 3D model

Pancreatic cancer (PC) remains one of the most challenging solid tumors to treat with a high unmet medical need as patients poorly respond to standard-of-care-therapies. Prominent desmoplastic reaction involving cancer-associated fibroblasts (CAFs) and the immune cells in the tumor microenvironment...

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Detalles Bibliográficos
Autores principales: Kuen, Janina, Darowski, Diana, Kluge, Tobias, Majety, Meher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531481/
https://www.ncbi.nlm.nih.gov/pubmed/28750018
http://dx.doi.org/10.1371/journal.pone.0182039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531481/
https://www.ncbi.nlm.nih.gov/pubmed/28750018
http://dx.doi.org/10.1371/journal.pone.0182039

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