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Identification of RNA biomarkers for chemical safety screening in mouse embryonic stem cells using RNA deep sequencing analysis

Although it is not yet possible to replace in vivo animal testing completely, the need for a more efficient method for toxicity testing, such as an in vitro cell-based assay, has been widely acknowledged. Previous studies have focused on mRNAs as biomarkers; however, recent studies have revealed tha...

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Detalles Bibliográficos
Autores principales: Tani, Hidenori, Takeshita, Jun-ichi, Aoki, Hiroshi, Nakamura, Kaoru, Abe, Ryosuke, Toyoda, Akinobu, Endo, Yasunori, Miyamoto, Sadaaki, Gamo, Masashi, Sato, Hiroaki, Torimura, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531504/
https://www.ncbi.nlm.nih.gov/pubmed/28750099
http://dx.doi.org/10.1371/journal.pone.0182032