A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP

Antimicrobial peptides (AMPs) are one of the most important defense mechanisms against bacterial infections in insects, plants, non-mammalian vertebrates, and mammals. In the present study, a class of synthetic AMPs was evaluated for anti-inflammatory activity. One cationic AMP, GW-A2, demonstrated...

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Detalles Bibliográficos
Autores principales: Li, Lan-Hui, Ju, Tz-Chuen, Hsieh, Chih-Yu, Dong, Wei-Chih, Chen, Wan-Tze, Hua, Kuo-Feng, Chen, Wei-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531531/
https://www.ncbi.nlm.nih.gov/pubmed/28750089
http://dx.doi.org/10.1371/journal.pone.0182057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531531/
https://www.ncbi.nlm.nih.gov/pubmed/28750089
http://dx.doi.org/10.1371/journal.pone.0182057

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