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Approaches to detect genetic effects that differ between two strata in genome-wide meta-analyses: Recommendations based on a systematic evaluation

Genome-wide association meta-analyses (GWAMAs) conducted separately by two strata have identified differences in genetic effects between strata, such as sex-differences for body fat distribution. However, there are several approaches to identify such differences and an uncertainty which approach to...

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Detalles Bibliográficos
Autores principales: Winkler, Thomas W., Justice, Anne E., Cupples, L. Adrienne, Kronenberg, Florian, Kutalik, Zoltán, Heid, Iris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531538/
https://www.ncbi.nlm.nih.gov/pubmed/28749953
http://dx.doi.org/10.1371/journal.pone.0181038