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Low calcium diet increases 4T1 mammary tumor carcinoma cell burden and bone pathology in mice

Breast cancer metastasizes to bone in the majority of patients with advanced disease. We investigated the effects of inadequate dietary calcium (Ca) on bone turnover, tumor growth, and bone response to tumor in tibia inoculated with 4T1 mammary carcinoma cells. Nine-month-old female Balb/c mice were...

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Detalles Bibliográficos
Autores principales: Wang, Wendan, Gordon, Jody L., Philbrick, Kenneth A., Yang, Xujuan, Branscum, Adam J., Löhr, Christiane V., Haschek, Wanda M., Turner, Russell T., Iwaniec, Urszula T., Helferich, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531562/
https://www.ncbi.nlm.nih.gov/pubmed/28750038
http://dx.doi.org/10.1371/journal.pone.0180886