Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration

It has long been postulated, although never directly demonstrated, that mitochondria are strategically positioned in the cytoplasm to meet local requirements for energy production. Here we show that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape of intracellul...

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Detalles Bibliográficos
Autores principales: Schuler, Max-Hinderk, Lewandowska, Agnieszka, Caprio, Giuseppe Di, Skillern, Wesley, Upadhyayula, Srigokul, Kirchhausen, Tom, Shaw, Janet M., Cunniff, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531732/
https://www.ncbi.nlm.nih.gov/pubmed/28615318
http://dx.doi.org/10.1091/mbc.E16-10-0741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531732/
https://www.ncbi.nlm.nih.gov/pubmed/28615318
http://dx.doi.org/10.1091/mbc.E16-10-0741

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