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PI3K class II α regulates δ-opioid receptor export from the trans-Golgi network

The interplay between signaling and trafficking by G protein–coupled receptors (GPCRs) has focused mainly on endocytic trafficking. Whether and how surface delivery of newly synthesized GPCRs is regulated by extracellular signals is less understood. Here we define a signaling-regulated checkpoint at...

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Detalles Bibliográficos
Autores principales: Shiwarski, Daniel J., Darr, Marlena, Telmer, Cheryl A., Bruchez, Marcel P., Puthenveedu, Manojkumar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531736/
https://www.ncbi.nlm.nih.gov/pubmed/28566554
http://dx.doi.org/10.1091/mbc.E17-01-0030