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High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast

In yeast, DNA breaks are usually repaired by homologous recombination (HR). An early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an intact DNA molecule. If the two strands of DNA are not identical, there...

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Detalles Bibliográficos
Autores principales: Yin, Yi, Dominska, Margaret, Yim, Eunice, Petes, Thomas D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531827/
https://www.ncbi.nlm.nih.gov/pubmed/28714850
http://dx.doi.org/10.7554/eLife.28069