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Skp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist

Castration-resistant prostate cancer (CRPC) remains a major clinical challenge due to the lack of effective targeted therapy for its treatment. The mechanism underlying how CRPC gains resistance towards hormone depletion and other forms of chemotherapy is poorly understood. Research on understanding...

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Detalles Bibliográficos
Autores principales: Ruan, Diane, He, Jiabei, Li, Chien-Feng, Lee, Hong-Jen, Liu, Jingxuan, Lin, Hui-Kuan, Chan, Chia-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532065/
https://www.ncbi.nlm.nih.gov/pubmed/28346424
http://dx.doi.org/10.1038/onc.2017.64