Co-dependency of PKCδ and K-Ras: Inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer

Recent studies suggest that the presence of a KRAS mutation may be insufficient for defining a clinically homogenous molecular group, as many KRAS mutant tumors lose reliance on K-Ras for survival. Identifying pathways that support K-Ras dependency may define clinically relevant KRAS sub-groups and...

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Detalles Bibliográficos
Autores principales: Ohm, Angela M., Tan, Aik-Choon, Heasley, Lynn E., Reyland, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532068/
https://www.ncbi.nlm.nih.gov/pubmed/28368426
http://dx.doi.org/10.1038/onc.2017.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532068/
https://www.ncbi.nlm.nih.gov/pubmed/28368426
http://dx.doi.org/10.1038/onc.2017.27

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