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Tannic acid as a plant-derived polyphenol exerts vasoprotection via enhancing KLF2 expression in endothelial cells

The transcription factor Kruppel-like factor 2 (KLF2) is a critical anti-inflammatory and anti-atherogenic molecule in vascular endothelium. Enhancing KLF2 expression and activity improves endothelial function and prevents atherosclerosis. However, the pharmacological and molecular regulators for KL...

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Detalles Bibliográficos
Autores principales: Xu, Yanni, Liu, Peng, Xu, Suowen, Koroleva, Marina, Zhang, Shuya, Si, Shuyi, Jin, Zheng Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532219/
https://www.ncbi.nlm.nih.gov/pubmed/28751752
http://dx.doi.org/10.1038/s41598-017-06803-x