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Mass-spectrometry analysis of modifications at DNA termini induced by DNA polymerases

Non-natural nucleotide substrates are widely used in the enzymatic synthesis of modified DNA. The terminal activity of polymerases in the presence of modified nucleotides is an important, but poorly characterized, aspect of enzymatic DNA synthesis. Here, we studied different types of polymerase acti...

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Detalles Bibliográficos
Autores principales: Smirnov, Igor P., Kolganova, Natalia A., Vasiliskov, Vadim A., Chudinov, Alexander V., Timofeev, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532294/
https://www.ncbi.nlm.nih.gov/pubmed/28751641
http://dx.doi.org/10.1038/s41598-017-06136-9