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Mass-spectrometry analysis of modifications at DNA termini induced by DNA polymerases
Non-natural nucleotide substrates are widely used in the enzymatic synthesis of modified DNA. The terminal activity of polymerases in the presence of modified nucleotides is an important, but poorly characterized, aspect of enzymatic DNA synthesis. Here, we studied different types of polymerase acti...
Autores principales: | Smirnov, Igor P., Kolganova, Natalia A., Vasiliskov, Vadim A., Chudinov, Alexander V., Timofeev, Edward N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532294/ https://www.ncbi.nlm.nih.gov/pubmed/28751641 http://dx.doi.org/10.1038/s41598-017-06136-9 |
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