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Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis

Megakaryocytopoiesis is a complex differentiation process driven by the hormone thrombopoietin by which haematopoietic progenitor cells give rise to megakaryocytes, the giant bone marrow cells that in turn break down to form blood platelets. The Tribbles Pseudokinase 3 gene (TRIB3) encodes a pleiotr...

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Detalles Bibliográficos
Autores principales: Butcher, Lee, Ahluwalia, Maninder, Örd, Tiit, Johnston, Jessica, Morris, Roger H., Kiss-Toth, Endre, Örd, Tõnis, Erusalimsky, Jorge D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532315/
https://www.ncbi.nlm.nih.gov/pubmed/28751721
http://dx.doi.org/10.1038/s41598-017-07096-w