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Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis
Megakaryocytopoiesis is a complex differentiation process driven by the hormone thrombopoietin by which haematopoietic progenitor cells give rise to megakaryocytes, the giant bone marrow cells that in turn break down to form blood platelets. The Tribbles Pseudokinase 3 gene (TRIB3) encodes a pleiotr...
Autores principales: | Butcher, Lee, Ahluwalia, Maninder, Örd, Tiit, Johnston, Jessica, Morris, Roger H., Kiss-Toth, Endre, Örd, Tõnis, Erusalimsky, Jorge D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532315/ https://www.ncbi.nlm.nih.gov/pubmed/28751721 http://dx.doi.org/10.1038/s41598-017-07096-w |
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