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A phase II study of irinotecan and pegylated liposomal doxorubicin in platinum-resistant recurrent ovarian cancer (Tohoku Gynecologic Cancer Unit 104 study)

PURPOSE: We report a phase II clinical study of the combination of irinotecan (CPT-11) and pegylated liposomal doxorubicin (PLD) in platinum- and taxane-resistant recurrent ovarian cancer, based on the recommended doses determined in a phase I trial. METHODS: PLD was administered intravenously at a...

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Detalles Bibliográficos
Autores principales: Shoji, Tadahiro, Takatori, Eriko, Omi, Hideo, Kagabu, Masahiro, Honda, Tatsuya, Futagami, Masayuki, Yokoyama, Yoshihito, Kaiho, Michiko, Tokunaga, Hideki, Otsuki, Takeo, Takano, Tadao, Yaegashi, Nobuo, Kojimahara, Takanobu, Ohta, Tsuyoshi, Nagase, Satoru, Soeda, Shu, Watanebe, Takafumi, Nishiyama, Hiroshi, Sugiyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532405/
https://www.ncbi.nlm.nih.gov/pubmed/28656383
http://dx.doi.org/10.1007/s00280-017-3363-0