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Methylene blue decreases mitochondrial lysine acetylation in the diabetic heart

Diabetic cardiomyopathy is preceded by mitochondrial alterations, and progresses to heart failure. We studied whether treatment with methylene blue (MB), a compound that was reported to serve as an alternate electron carrier within the mitochondrial electron transport chain (ETC), improves mitochond...

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Detalles Bibliográficos
Autores principales: Berthiaume, Jessica M., Hsiung, Chia-heng, Austin, Alison B., McBrayer, Sean P., Depuydt, Mikayla M., Chandler, Margaret P., Miyagi, Masaru, Rosca, Mariana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532421/
https://www.ncbi.nlm.nih.gov/pubmed/28303408
http://dx.doi.org/10.1007/s11010-017-2993-1