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Prevention of tumour cell apoptosis associated with sustained protein kinase B phosphorylation is more sensitive to regulation by insulin signalling than stimulation of proliferation and extracellular signal-regulated kinase

Insulin controls blood glucose while insulin-like growth factor (IGF) 1 is an important growth factor. Interestingly, both hormones have overlapping bioactivities and can activate the same intracellular signal transduction cascades. Growth control (mainly by IGF1) and metabolic function (predominant...

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Detalles Bibliográficos
Autores principales: Schmid, Christoph, Ghirlanda, Claudia, Niessen, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532423/
https://www.ncbi.nlm.nih.gov/pubmed/28316059
http://dx.doi.org/10.1007/s11010-017-2996-y