α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA(B) receptors

OBJECTIVE: α-Conotoxin Vc1.1 is a small disulfide-bonded peptide from the venom of the marine cone snail Conus victoriae. Vc1.1 has antinociceptive actions in animal models of neuropathic pain, but its applicability to inhibiting human dorsal root ganglion (DRG) neuroexcitability and reducing chroni...

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Detalles Bibliográficos
Autores principales: Castro, Joel, Harrington, Andrea M, Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E, Craik, David J, Adams, David J, Brierley, Stuart M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Neurogastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532460/
https://www.ncbi.nlm.nih.gov/pubmed/26887818
http://dx.doi.org/10.1136/gutjnl-2015-310971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532460/
https://www.ncbi.nlm.nih.gov/pubmed/26887818
http://dx.doi.org/10.1136/gutjnl-2015-310971

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