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Nonspecific block of voltage‐gated potassium channels has greater effect on distal schaffer collaterals than proximal schaffer collaterals during periods of high activity

Previous studies established different responses between proximal and distal portions of Schaffer collateral axons during high‐frequency and burst stimulation, with distal axons demonstrating biphasic changes in excitability (hyperexcitability followed by depression), but proximal axons showing only...

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Detalles Bibliográficos
Autores principales: Owen, Benjamin, Reddy, Rishi, Grover, Lawrence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532488/
https://www.ncbi.nlm.nih.gov/pubmed/28747510
http://dx.doi.org/10.14814/phy2.13354