The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer

DNA double-strand breaks (DSBs) are deleterious DNA lesions that if left unrepaired or are misrepaired, potentially result in chromosomal aberrations, known drivers of carcinogenesis. Pathways that direct the repair of DSBs are traditionally believed to be guardians of the genome as they protect cel...

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Detalles Bibliográficos
Autores principales: Sishc, Brock J., Davis, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532617/
https://www.ncbi.nlm.nih.gov/pubmed/28684677
http://dx.doi.org/10.3390/cancers9070081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532617/
https://www.ncbi.nlm.nih.gov/pubmed/28684677
http://dx.doi.org/10.3390/cancers9070081

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