SIRT3: Oncogene and Tumor Suppressor in Cancer

Sirtuin 3 (SIRT3), the major deacetylase in mitochondria, plays a crucial role in modulating oxygen reactive species (ROS) and limiting the oxidative damage in cellular components. SIRT3 targets different enzymes which regulate mitochondrial metabolism and participate in ROS detoxification, such as...

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Detalles Bibliográficos
Autores principales: Torrens-Mas, Margalida, Oliver, Jordi, Roca, Pilar, Sastre-Serra, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532626/
https://www.ncbi.nlm.nih.gov/pubmed/28704962
http://dx.doi.org/10.3390/cancers9070090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532626/
https://www.ncbi.nlm.nih.gov/pubmed/28704962
http://dx.doi.org/10.3390/cancers9070090

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