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SIRT3: Oncogene and Tumor Suppressor in Cancer
Sirtuin 3 (SIRT3), the major deacetylase in mitochondria, plays a crucial role in modulating oxygen reactive species (ROS) and limiting the oxidative damage in cellular components. SIRT3 targets different enzymes which regulate mitochondrial metabolism and participate in ROS detoxification, such as...
Autores principales: | Torrens-Mas, Margalida, Oliver, Jordi, Roca, Pilar, Sastre-Serra, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532626/ https://www.ncbi.nlm.nih.gov/pubmed/28704962 http://dx.doi.org/10.3390/cancers9070090 |
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