Responses to crizotinib and chemotherapy in patients with lung adenocarcinoma harboring a concomitant EGFR mutation and ALK gene rearrangement: A case report and review of the literature

Previous studies have indicated that, in lung cancers, the gene rearrangement of ALK is mutually exclusive with mutations in the epidermal growth factor receptor (EGFR) gene. However, the coexistence of EML4-ALK fusions and EGFR mutations (double positive) has been occasionally reported, with freque...

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Detalles Bibliográficos
Autores principales: Li, Yuping, Su, Shanshan, Cai, Guoping, Lin, Quan, Zhou, Ying, Ouyang, Jinsheng, Chen, Bicheng, Ye, Junru, Wu, Xiuling, Chen, Chengshui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532680/
https://www.ncbi.nlm.nih.gov/pubmed/28781781
http://dx.doi.org/10.3892/mco.2017.1306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532680/
https://www.ncbi.nlm.nih.gov/pubmed/28781781
http://dx.doi.org/10.3892/mco.2017.1306

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