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1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

[Image: see text] The essential biological roles played by glycosidases, coupled to the diverse therapeutic benefits of pharmacologically targeting these enzymes, provide considerable motivation for the development of new inhibitor classes. Cyclophellitol epoxides and aziridines are recently establi...

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Detalles Bibliográficos
Autores principales: Artola, Marta, Wu, Liang, Ferraz, Maria J., Kuo, Chi-Lin, Raich, Lluís, Breen, Imogen Z., Offen, Wendy A., Codée, Jeroen D. C., van der Marel, Gijsbert A., Rovira, Carme, Aerts, Johannes M. F. G., Davies, Gideon J., Overkleeft, Herman S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532717/
https://www.ncbi.nlm.nih.gov/pubmed/28776021
http://dx.doi.org/10.1021/acscentsci.7b00214