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l1kdeconv: an R package for peak calling analysis with LINCS L1000 data

BACKGROUND: LINCS L1000 is a high-throughput technology that allows gene expression measurement in a large number of assays. However, to fit the measurements of ~1000 genes in the ~500 color channels of LINCS L1000, every two landmark genes are designed to share a single channel. Thus, a deconvoluti...

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Detalles Bibliográficos
Autores principales: Li, Zhao, Li, Jin, Yu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532784/
https://www.ncbi.nlm.nih.gov/pubmed/28750623
http://dx.doi.org/10.1186/s12859-017-1767-9