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Use of p53‐Silenced Endothelial Progenitor Cells to Treat Ischemia in Diabetic Peripheral Vascular Disease

BACKGROUND: Peripheral vascular disease is a major diabetes mellitus‐related complication. In this study, we noted that expressions of proapoptotic p53 gene and its downstream cascade gene such as p21 are upregulated in hyperglycemia. Therefore, we investigated whether p53‐ and p21‐silenced endothel...

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Detalles Bibliográficos
Autores principales: Kundu, Nabanita, Domingues, Cleyton C., Chou, Cyril, Ahmadi, Neeki, Houston, Sara, Jerry, D. Joseph, Sen, Sabyasachi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533015/
https://www.ncbi.nlm.nih.gov/pubmed/28365567
http://dx.doi.org/10.1161/JAHA.116.005146