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An NPPB Promoter Polymorphism Associated With Elevated N‐Terminal pro–B‐Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality

BACKGROUND: Elevated B‐type natriuretic peptide (BNP) levels are associated with heart failure and increased mortality in the general population. We investigated rs198389, a functional variant in the promoter region of the BNP gene (NPPB), in patients from the Atherosclerosis Risk in Communities Stu...

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Detalles Bibliográficos
Autores principales: Seidelmann, Sara B., Vardeny, Orly, Claggett, Brian, Yu, Bing, Shah, Amil M., Ballantyne, Christie M., Selvin, Elizabeth, MacRae, Calum A., Boerwinkle, Eric, Solomon, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533018/
https://www.ncbi.nlm.nih.gov/pubmed/28341776
http://dx.doi.org/10.1161/JAHA.116.005257