Altered MicroRNA Expression Is Responsible for the Pro‐Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves

BACKGROUND: The transition of aortic valve interstitial cells (AVICs) to myofibroblastic and osteoblast‐like phenotypes plays a critical role in calcific aortic valve disease progression. Several microRNAs (miRs) are implicated in stem cell differentiation into osteoblast. We hypothesized that an ep...

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Detalles Bibliográficos
Autores principales: Song, Rui, Fullerton, David A., Ao, Lihua, Zhao, Ke‐seng, Reece, T. Brett, Cleveland, Joseph C., Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533027/
https://www.ncbi.nlm.nih.gov/pubmed/28438736
http://dx.doi.org/10.1161/JAHA.116.005364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533027/
https://www.ncbi.nlm.nih.gov/pubmed/28438736
http://dx.doi.org/10.1161/JAHA.116.005364

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