Ion mobility spectrometry combined with ultra performance liquid chromatography/mass spectrometry for metabolic phenotyping of urine: Effects of column length, gradient duration and ion mobility spectrometry on metabolite detection

The need for rapid and efficient high throughput metabolic phenotyping (metabotyping) in metabolomic/metabonomic studies often requires compromises to be made between analytical speed and metabolome coverage. Here the effect of column length (150, 75 and 30 mm) and gradient duration (15, 7.5 and 3 m...

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Detalles Bibliográficos
Autores principales: Rainville, Paul D., Wilson, Ian D., Nicholson, Jeremy K., Issacs, Giorgis, Mullin, Lauren, Langridge, James I., Plumb, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533171/
https://www.ncbi.nlm.nih.gov/pubmed/28734348
http://dx.doi.org/10.1016/j.aca.2017.06.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533171/
https://www.ncbi.nlm.nih.gov/pubmed/28734348
http://dx.doi.org/10.1016/j.aca.2017.06.020

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