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Ion mobility spectrometry combined with ultra performance liquid chromatography/mass spectrometry for metabolic phenotyping of urine: Effects of column length, gradient duration and ion mobility spectrometry on metabolite detection
The need for rapid and efficient high throughput metabolic phenotyping (metabotyping) in metabolomic/metabonomic studies often requires compromises to be made between analytical speed and metabolome coverage. Here the effect of column length (150, 75 and 30 mm) and gradient duration (15, 7.5 and 3 m...
Autores principales: | Rainville, Paul D., Wilson, Ian D., Nicholson, Jeremy K., Issacs, Giorgis, Mullin, Lauren, Langridge, James I., Plumb, Robert S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533171/ https://www.ncbi.nlm.nih.gov/pubmed/28734348 http://dx.doi.org/10.1016/j.aca.2017.06.020 |
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