IP6K1 Reduces Mesenchymal Stem/Stromal Cell Fitness and Potentiates High Fat Diet‐Induced Skeletal Involution

Mesenchymal stem/stromal cells (MSCs) are the predominant source of bone and adipose tissue in adult bone marrow and play a critical role in skeletal homeostasis. Age‐induced changes in bone marrow favor adipogenesis over osteogenesis leading to skeletal involution and increased marrow adiposity so...

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Detalles Bibliográficos
Autores principales: Boregowda, Siddaraju V., Ghoshal, Sarbani, Booker, Cori N., Krishnappa, Veena, Chakraborty, Anutosh, Phinney, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Tissue‐Specific Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533188/
https://www.ncbi.nlm.nih.gov/pubmed/28577302
http://dx.doi.org/10.1002/stem.2645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533188/
https://www.ncbi.nlm.nih.gov/pubmed/28577302
http://dx.doi.org/10.1002/stem.2645

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