Acidosis counteracts itch tachyphylaxis to consecutive pruritogen exposure dependent on acid-sensing ion channel 3

Tachyphylaxis of itch refers to a markedly reduced scratching response to consecutive exposures of a pruritogen, a process thought to protect against tissue damage by incessant scratching and to become disrupted in chronic itch. Here, we report that a strong stimulation of the Mas-related G-protein-...

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Detalles Bibliográficos
Autores principales: Jiang, Yi-Ming, Huang, Chen, Peng, Zhong, Han, Shao-Ling, Li, Wei-Guang, Zhu, Michael Xi, Xu, Tian-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533257/
https://www.ncbi.nlm.nih.gov/pubmed/28745101
http://dx.doi.org/10.1177/1744806917721114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533257/
https://www.ncbi.nlm.nih.gov/pubmed/28745101
http://dx.doi.org/10.1177/1744806917721114

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