Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin

The aim of this study was to assess any potential additive effects of a treatment combining aliskiren with paricalcitol on reducing renal fibrosis. C57BL/6J mice were treated individually with aliskiren and/or paricalcitol until 7 days after initiation of unilateral ureteral obstruction (UUO).In obs...

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Detalles Bibliográficos
Autores principales: Chung, Sungjin, Kim, Soojeong, Kim, Minyoung, Koh, Eun Sil, Shin, Seok Joon, Park, Cheol Whee, Chang, Yoon Sik, Kim, Ho-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533315/
https://www.ncbi.nlm.nih.gov/pubmed/28753620
http://dx.doi.org/10.1371/journal.pone.0181757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533315/
https://www.ncbi.nlm.nih.gov/pubmed/28753620
http://dx.doi.org/10.1371/journal.pone.0181757

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