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NS3 genomic sequencing and phylogenetic analysis as alternative to a commercially available assay to reliably determine hepatitis C virus subtypes 1a and 1b

OBJECTIVE: To evaluate the use of hepatitis C virus (HCV) NS3 sequencing as alternative to the comercially available Versant HCV 2.0 reverse hybridization line-probe assay (LiPA 2.0) to determine HCV genotype 1 (HCV-1) subtypes. PATIENTS AND METHODS: A cohort of 104 patients infected by HCV-1 accord...

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Detalles Bibliográficos
Autores principales: Neukam, Karin, Martínez, Alfredo P., Culasso, Andrés C. A., Ridruejo, Ezequiel, García, Gabriel, Di Lello, Federico A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533332/
https://www.ncbi.nlm.nih.gov/pubmed/28753662
http://dx.doi.org/10.1371/journal.pone.0182193