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A new computational strategy for identifying essential proteins based on network topological properties and biological information
Essential proteins are the proteins that are indispensable to the survival and development of an organism. Deleting a single essential protein will cause lethality or infertility. Identifying and analysing essential proteins are key to understanding the molecular mechanisms of living cells. There ar...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533339/ https://www.ncbi.nlm.nih.gov/pubmed/28753682 http://dx.doi.org/10.1371/journal.pone.0182031 |