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SOCS1 function in BCR-ABL mediated myeloproliferative disease is dependent on the cytokine environment
Treatment with tyrosine kinase inhibitors is the standard of care for Philadelphia chromosome positive leukemias. However the eradication of leukemia initiating cells remains a challenge. Circumstantial evidence suggests that the cytokine microenvironment may play a role in BCR-ABL mediated leukemog...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533340/ https://www.ncbi.nlm.nih.gov/pubmed/28753604 http://dx.doi.org/10.1371/journal.pone.0180401 |