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SOCS1 function in BCR-ABL mediated myeloproliferative disease is dependent on the cytokine environment

Treatment with tyrosine kinase inhibitors is the standard of care for Philadelphia chromosome positive leukemias. However the eradication of leukemia initiating cells remains a challenge. Circumstantial evidence suggests that the cytokine microenvironment may play a role in BCR-ABL mediated leukemog...

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Detalles Bibliográficos
Autores principales:	Demirel, Özlem, Balló, Olivier, Reddy, Pavankumar N. G., Vakhrusheva, Olesya, Zhang, Jing, Eichler, Astrid, Fernandes, Ramona, Badura, Susanne, Serve, Hubert, Brandts, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533340/ https://www.ncbi.nlm.nih.gov/pubmed/28753604 http://dx.doi.org/10.1371/journal.pone.0180401

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