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Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer
Pyruvate kinase M2 (PKM2) regulates glycolysis and oxidative phosphorylation; however, the role of PKM2 in ovarian cancer remains largely unknown. We investigated whether ovarian cancer metabolism could provide insight into the development of therapeutic strategies. We performed immunohistochemical...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533430/ https://www.ncbi.nlm.nih.gov/pubmed/28753677 http://dx.doi.org/10.1371/journal.pone.0182166 |