Cargando…
Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer
Pyruvate kinase M2 (PKM2) regulates glycolysis and oxidative phosphorylation; however, the role of PKM2 in ovarian cancer remains largely unknown. We investigated whether ovarian cancer metabolism could provide insight into the development of therapeutic strategies. We performed immunohistochemical...
Autores principales: | Chao, Tai-Kuang, Huang, Tien-Shuo, Liao, Yu-Ping, Huang, Rui-Lan, Su, Po-Hsuan, Shen, Hueng-Yuan, Lai, Hung-Cheng, Wang, Yu-Chi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533430/ https://www.ncbi.nlm.nih.gov/pubmed/28753677 http://dx.doi.org/10.1371/journal.pone.0182166 |
Ejemplares similares
-
Pyruvate Kinase M2 Expression: A Potential Metabolic Biomarker to Differentiate Endometrial Precancer and Cancer that is Associated with Poor Outcomes in Endometrial Carcinoma
por: Lai, Yu-Ju, et al.
Publicado: (2019) -
Overexpression of Pyruvate Dehydrogenase Kinase-3 Predicts Poor Prognosis in Urothelial Carcinoma
por: Kuo, Yu-Hsuan, et al.
Publicado: (2021) -
Preclinical evaluation of a nanoformulated antihelminthic, niclosamide, in ovarian cancer
por: Lin, Chi-Kang, et al.
Publicado: (2016) -
An epigenetic signature of adhesion molecules predicts poor prognosis of ovarian cancer patients
por: Chang, Ping-Ying, et al.
Publicado: (2017) -
Ovarian cancer stem-like cells with induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor
por: Liu, Kuei-Chun, et al.
Publicado: (2013)