Solution NMR structure of the TRIM21 B-box2 and identification of residues involved in its interaction with the RING domain

Tripartite motif-containing (TRIM) proteins are defined by the sequential arrangement of RING, B-box and coiled-coil domains (RBCC), where the B-box domain is a unique feature of the TRIM protein family. TRIM21 is an E3 ubiquitin-protein ligase implicated in innate immune signaling by acting as an a...

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Detalles Bibliográficos
Autores principales: Wallenhammar, Amélie, Anandapadamanaban, Madhanagopal, Lemak, Alexander, Mirabello, Claudio, Lundström, Patrik, Wallner, Björn, Sunnerhagen, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533445/
https://www.ncbi.nlm.nih.gov/pubmed/28753623
http://dx.doi.org/10.1371/journal.pone.0181551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533445/
https://www.ncbi.nlm.nih.gov/pubmed/28753623
http://dx.doi.org/10.1371/journal.pone.0181551

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