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Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis
[Image: see text] Naturally split inteins have found widespread use in chemical biology due to their ability to drive the ligation of separately expressed polypeptides through a process termed protein trans-splicing (PTS). In this study, we harness PTS by rendering association of split intein fragme...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533455/ https://www.ncbi.nlm.nih.gov/pubmed/28562027 http://dx.doi.org/10.1021/jacs.7b02618 |